Novel Implant Coating Agent Promotes Gene Expression of Osteogenic Markers in Rats during Early Osseointegration
Identifieur interne : 003130 ( Main/Exploration ); précédent : 003129; suivant : 003131Novel Implant Coating Agent Promotes Gene Expression of Osteogenic Markers in Rats during Early Osseointegration
Auteurs : Kostas Bougas [Suède] ; Ryo Jimbo [Suède] ; Ying Xue [Norvège] ; Kamal Mustafa [Norvège] ; Ann Wennerberg [Suède]Source :
- International Journal of Biomaterials [ 1687-8787 ] ; 2012.
Abstract
The aim of this study was to evaluate the early bone response around laminin-1-coated titanium implants. Forty-five rats distributed in three equally sized groups were provided with one control (turned) and one test (laminin-1-coated) implant and were sacrificed after 3, 7, and 21 days. Real-time reverse-transcriptase polymerase chain reaction was performed for osteoblast markers (alkaline phosphatase, runt-related transcription factor 2, osteocalcin, type I collagen, and bone morphogenic protein 2), osteoclast markers (cathepsin K and tartrate-resistant acid phosphatase), inflammation markers (tumor necrosis factor
Url:
DOI: 10.1155/2012/579274
PubMed: 23193408
PubMed Central: 3501934
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Novel Implant Coating Agent Promotes Gene Expression of Osteogenic Markers in Rats during Early Osseointegration</title><author><name sortKey="Bougas, Kostas" sort="Bougas, Kostas" uniqKey="Bougas K" first="Kostas" last="Bougas">Kostas Bougas</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Prosthodontics, Faculty of Odontology, Malmö University, 205 06 Malmö, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Prosthodontics, Faculty of Odontology, Malmö University, 205 06 Malmö</wicri:regionArea><wicri:noRegion>205 06 Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Jimbo, Ryo" sort="Jimbo, Ryo" uniqKey="Jimbo R" first="Ryo" last="Jimbo">Ryo Jimbo</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Prosthodontics, Faculty of Odontology, Malmö University, 205 06 Malmö, Sweden</nlm:aff><country 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id="I2">Department of Clinical Dentistry, Center for Clinical Research, Faculty of Medicine and Dentistry, University of Bergen, Årstadveien 17, 5009 Bergen, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Clinical Dentistry, Center for Clinical Research, Faculty of Medicine and Dentistry, University of Bergen, Årstadveien 17, 5009 Bergen</wicri:regionArea><wicri:noRegion>5009 Bergen</wicri:noRegion></affiliation></author><author><name sortKey="Wennerberg, Ann" sort="Wennerberg, Ann" uniqKey="Wennerberg A" first="Ann" last="Wennerberg">Ann Wennerberg</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Prosthodontics, Faculty of Odontology, Malmö University, 205 06 Malmö, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Prosthodontics, Faculty of Odontology, Malmö University, 205 06 Malmö</wicri:regionArea><wicri:noRegion>205 06 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K:novel:implant:coating</idno><idno type="wicri:Area/Main/Merge">003145</idno><idno type="wicri:Area/Main/Curation">003130</idno><idno type="wicri:Area/Main/Exploration">003130</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Novel Implant Coating Agent Promotes Gene Expression of Osteogenic Markers in Rats during Early Osseointegration</title><author><name sortKey="Bougas, Kostas" sort="Bougas, Kostas" uniqKey="Bougas K" first="Kostas" last="Bougas">Kostas Bougas</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Prosthodontics, Faculty of Odontology, Malmö University, 205 06 Malmö, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Prosthodontics, Faculty of Odontology, Malmö University, 205 06 Malmö</wicri:regionArea><wicri:noRegion>205 06 Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Jimbo, Ryo" sort="Jimbo, Ryo" uniqKey="Jimbo R" first="Ryo" last="Jimbo">Ryo Jimbo</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Prosthodontics, Faculty of Odontology, Malmö University, 205 06 Malmö, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Prosthodontics, Faculty of Odontology, Malmö University, 205 06 Malmö</wicri:regionArea><wicri:noRegion>205 06 Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Xue, Ying" sort="Xue, Ying" uniqKey="Xue Y" first="Ying" last="Xue">Ying Xue</name><affiliation wicri:level="1"><nlm:aff id="I2">Department of Clinical Dentistry, Center for Clinical Research, Faculty of Medicine and Dentistry, University of Bergen, Årstadveien 17, 5009 Bergen, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Clinical Dentistry, Center for Clinical Research, Faculty of Medicine and Dentistry, University of Bergen, Årstadveien 17, 5009 Bergen</wicri:regionArea><wicri:noRegion>5009 Bergen</wicri:noRegion></affiliation></author><author><name sortKey="Mustafa, Kamal" sort="Mustafa, Kamal" uniqKey="Mustafa K" first="Kamal" last="Mustafa">Kamal Mustafa</name><affiliation wicri:level="1"><nlm:aff id="I2">Department of Clinical Dentistry, Center for Clinical Research, Faculty of Medicine and Dentistry, University of Bergen, Årstadveien 17, 5009 Bergen, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Clinical Dentistry, Center for Clinical Research, Faculty of Medicine and Dentistry, University of Bergen, Årstadveien 17, 5009 Bergen</wicri:regionArea><wicri:noRegion>5009 Bergen</wicri:noRegion></affiliation></author><author><name sortKey="Wennerberg, Ann" sort="Wennerberg, Ann" uniqKey="Wennerberg A" first="Ann" last="Wennerberg">Ann Wennerberg</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Prosthodontics, Faculty of Odontology, Malmö University, 205 06 Malmö, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Prosthodontics, Faculty of Odontology, Malmö University, 205 06 Malmö</wicri:regionArea><wicri:noRegion>205 06 Malmö</wicri:noRegion></affiliation></author></analytic><series><title level="j">International Journal of Biomaterials</title><idno type="ISSN">1687-8787</idno><idno type="eISSN">1687-8795</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The aim of this study was to evaluate the early bone response around laminin-1-coated titanium implants. Forty-five rats distributed in three equally sized groups were provided with one control (turned) and one test (laminin-1-coated) implant and were sacrificed after 3, 7, and 21 days. Real-time reverse-transcriptase polymerase chain reaction was performed for osteoblast markers (alkaline phosphatase, runt-related transcription factor 2, osteocalcin, type I collagen, and bone morphogenic protein 2), osteoclast markers (cathepsin K and tartrate-resistant acid phosphatase), inflammation markers (tumor necrosis factor <italic><italic>α</italic></italic>, interleukin 1<italic><italic>β</italic></italic> and interleukin 10), and integrin <italic><italic>β</italic></italic>1. Bone implant contact (BIC) and bone area (BA) were assessed and compared to the gene expression. After 3 days, the expression of bone markers was higher for the control group. After 7 days, the expression of integrin <italic><italic>β</italic></italic>1 and osteogenic markers was enhanced for the test group, while cathepsin K and inflammation markers were down-regulated. No significant differences in BIC or BA were detected between test and control at any time point. As a conclusion, implant coating with laminin-1 altered gene expression in the bone-implant interface. However, traditional evaluation methods, as histomorphometry, were not adequately sensitive to detect such changes due to the short follow-up time.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Jemt, T" uniqKey="Jemt T">T Jemt</name></author><author><name sortKey="Johansson, J" uniqKey="Johansson J">J Johansson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jemt, T" uniqKey="Jemt T">T Jemt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey=" Strand, P" uniqKey=" Strand P">P Åstrand</name></author><author><name sortKey="Ahlqvist, J" uniqKey="Ahlqvist J">J Ahlqvist</name></author><author><name sortKey="Gunne, J" uniqKey="Gunne J">J Gunne</name></author><author><name sortKey="Nilson, H" uniqKey="Nilson H">H Nilson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Williams, Df" uniqKey="Williams D">DF Williams</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jungner, M" uniqKey="Jungner M">M Jungner</name></author><author><name sortKey="Lundqvist, P" uniqKey="Lundqvist P">P Lundqvist</name></author><author><name sortKey="Lundgren, S" uniqKey="Lundgren S">S Lundgren</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Friberg, B" uniqKey="Friberg B">B Friberg</name></author><author><name sortKey="Jemt, T" uniqKey="Jemt T">T Jemt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brechter, M" uniqKey="Brechter M">M Brechter</name></author><author><name sortKey="Nilson, H" uniqKey="Nilson H">H Nilson</name></author><author><name sortKey="Lundgren, S" uniqKey="Lundgren S">S Lundgren</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Quirynen, M" uniqKey="Quirynen M">M Quirynen</name></author><author><name sortKey="Van Assche, N" uniqKey="Van Assche N">N Van Assche</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Albouy, Jp" uniqKey="Albouy J">JP Albouy</name></author><author><name sortKey="Abrahamsson, I" uniqKey="Abrahamsson I">I Abrahamsson</name></author><author><name sortKey="Persson, Lg" uniqKey="Persson L">LG Persson</name></author><author><name sortKey="Berglundh, T" uniqKey="Berglundh T">T Berglundh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Albouy, Jp" uniqKey="Albouy J">JP Albouy</name></author><author><name sortKey="Abrahamsson, I" uniqKey="Abrahamsson I">I Abrahamsson</name></author><author><name sortKey="Persson, Lg" uniqKey="Persson L">LG Persson</name></author><author><name sortKey="Berglundh, T" uniqKey="Berglundh T">T Berglundh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Albouy, Jp" uniqKey="Albouy J">JP Albouy</name></author><author><name sortKey="Abrahamsson, I" uniqKey="Abrahamsson I">I Abrahamsson</name></author><author><name sortKey="Berglundh, T" uniqKey="Berglundh T">T Berglundh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Albouy, Jp" uniqKey="Albouy J">JP Albouy</name></author><author><name sortKey="Abrahamsson, I" uniqKey="Abrahamsson I">I Abrahamsson</name></author><author><name sortKey="Persson, Lg" uniqKey="Persson L">LG Persson</name></author><author><name sortKey="Berglundh, T" uniqKey="Berglundh T">T Berglundh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Frojd, V" uniqKey="Frojd V">V Fröjd</name></author><author><name sortKey="Chavez De Paz, L" uniqKey="Chavez De Paz L">L Chávez de Paz</name></author><author><name sortKey="Andersson, M" uniqKey="Andersson M">M Andersson</name></author><author><name sortKey="Wennerberg, A" uniqKey="Wennerberg A">A Wennerberg</name></author><author><name sortKey="Davies, Jr" uniqKey="Davies J">JR Davies</name></author><author><name sortKey="Svens Ter, G" uniqKey="Svens Ter G">G Svensäter</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wikesjo, Ume" uniqKey="Wikesjo U">UME Wikesjö</name></author><author><name sortKey="Huang, Yh" uniqKey="Huang Y">YH Huang</name></author><author><name sortKey="Xiropaidis, Av" uniqKey="Xiropaidis A">AV Xiropaidis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thorey, F" uniqKey="Thorey F">F Thorey</name></author><author><name sortKey="Menzel, H" uniqKey="Menzel H">H Menzel</name></author><author><name sortKey="Lorenz, C" uniqKey="Lorenz C">C Lorenz</name></author><author><name sortKey="Gross, G" uniqKey="Gross G">G Gross</name></author><author><name sortKey="Hoffmann, A" uniqKey="Hoffmann A">A Hoffmann</name></author><author><name sortKey="Windhagen, H" uniqKey="Windhagen H">H Windhagen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Abtahi, J" uniqKey="Abtahi J">J Abtahi</name></author><author><name sortKey="Tengvall, P" uniqKey="Tengvall P">P Tengvall</name></author><author><name sortKey="Aspenberg, P" uniqKey="Aspenberg P">P Aspenberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jimbo, R" uniqKey="Jimbo R">R Jimbo</name></author><author><name sortKey="Sawase, T" uniqKey="Sawase T">T Sawase</name></author><author><name sortKey="Shibata, Y" uniqKey="Shibata Y">Y Shibata</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nyan, M" uniqKey="Nyan M">M Nyan</name></author><author><name sortKey="Sato, D" uniqKey="Sato D">D Sato</name></author><author><name sortKey="Kihara, H" uniqKey="Kihara H">H Kihara</name></author><author><name sortKey="Machida, T" uniqKey="Machida T">T MacHida</name></author><author><name sortKey="Ohya, K" uniqKey="Ohya K">K Ohya</name></author><author><name sortKey="Kasugai, S" uniqKey="Kasugai S">S Kasugai</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Colognato, H" uniqKey="Colognato H">H Colognato</name></author><author><name sortKey="Yurchenco, Pd" uniqKey="Yurchenco P">PD Yurchenco</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Roche, P" uniqKey="Roche P">P Roche</name></author><author><name sortKey="Goldberg, Ha" uniqKey="Goldberg H">HA Goldberg</name></author><author><name sortKey="Delmas, Pd" uniqKey="Delmas P">PD Delmas</name></author><author><name sortKey="Malaval, L" uniqKey="Malaval L">L Malaval</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Roche, P" uniqKey="Roche P">P Roche</name></author><author><name sortKey="Rousselle, P" uniqKey="Rousselle P">P Rousselle</name></author><author><name sortKey="Lissitzky, Jc" uniqKey="Lissitzky J">JC Lissitzky</name></author><author><name sortKey="Delmas, Pd" uniqKey="Delmas P">PD Delmas</name></author><author><name sortKey="Malaval, L" uniqKey="Malaval L">L Malaval</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vukicevic, S" uniqKey="Vukicevic S">S Vukicevic</name></author><author><name sortKey="Luyten, Fp" uniqKey="Luyten F">FP Luyten</name></author><author><name sortKey="Kleinman, Hk" uniqKey="Kleinman H">HK Kleinman</name></author><author><name sortKey="Reddi, Ah" uniqKey="Reddi A">AH Reddi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bougas, K" uniqKey="Bougas K">K Bougas</name></author><author><name sortKey="Franke Stenport, V" uniqKey="Franke Stenport V">V Franke Stenport</name></author><author><name sortKey="Currie, F" uniqKey="Currie F">F Currie</name></author><author><name sortKey="Wennerberg, A" uniqKey="Wennerberg A">A Wennerberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bougas, K" uniqKey="Bougas K">K Bougas</name></author><author><name sortKey="Franke Stenport, V" uniqKey="Franke Stenport V">V Franke Stenport</name></author><author><name sortKey="Tengvall, P" uniqKey="Tengvall P">P Tengvall</name></author><author><name sortKey="Currie, F" uniqKey="Currie F">F Currie</name></author><author><name sortKey="Wennerberg, A" uniqKey="Wennerberg A">A Wennerberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brunette, Dm" uniqKey="Brunette D">DM Brunette</name></author><author><name sortKey="Tengvall, P" uniqKey="Tengvall P">P Tengvall</name></author><author><name sortKey="Textor, M" uniqKey="Textor M">M Textor</name></author><author><name sortKey="Thomsen, P" uniqKey="Thomsen P">P Thomsen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fang, F" uniqKey="Fang F">F Fang</name></author><author><name sortKey="Satulovsky, J" uniqKey="Satulovsky J">J Satulovsky</name></author><author><name sortKey="Szleifer, I" uniqKey="Szleifer I">I Szleifer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Linderb Ck, P" uniqKey="Linderb Ck P">P Linderbäck</name></author><author><name sortKey="Harmankaya, N" uniqKey="Harmankaya N">N Harmankaya</name></author><author><name sortKey="Askendal, A" uniqKey="Askendal A">A Askendal</name></author><author><name sortKey="Areva, S" uniqKey="Areva S">S Areva</name></author><author><name sortKey="Lausmaa, J" uniqKey="Lausmaa J">J Lausmaa</name></author><author><name sortKey="Tengvall, P" uniqKey="Tengvall P">P Tengvall</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mccrackin, Fl" uniqKey="Mccrackin F">FL McCrackin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wennerberg, A" uniqKey="Wennerberg A">A Wennerberg</name></author><author><name sortKey="Albrektsson, T" uniqKey="Albrektsson T">T Albrektsson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schmittgen, Td" uniqKey="Schmittgen T">TD Schmittgen</name></author><author><name sortKey="Livak, Kj" uniqKey="Livak K">KJ Livak</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Donath, K" uniqKey="Donath K">K Donath</name></author><author><name sortKey="Breuner, G" uniqKey="Breuner G">G Breuner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Johansson, Cb" uniqKey="Johansson C">CB Johansson</name></author><author><name sortKey="Albrektsson, T" uniqKey="Albrektsson T">T Albrektsson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Johansson, Cb" uniqKey="Johansson C">CB Johansson</name></author><author><name sortKey="Sennerby, L" uniqKey="Sennerby L">L Sennerby</name></author><author><name sortKey="Albrektsson, T" uniqKey="Albrektsson T">T Albrektsson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wennerberg, A" uniqKey="Wennerberg A">A Wennerberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Omar, O" uniqKey="Omar O">O Omar</name></author><author><name sortKey="Svensson, S" uniqKey="Svensson S">S Svensson</name></author><author><name sortKey="Zoric, N" uniqKey="Zoric N">N Zoric</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Omar, Om" uniqKey="Omar O">OM Omar</name></author><author><name sortKey="Lenner S, Me" uniqKey="Lenner S M">ME Lennerås</name></author><author><name sortKey="Suska, F" uniqKey="Suska F">F Suska</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Omar, O" uniqKey="Omar O">O Omar</name></author><author><name sortKey="Suska, F" uniqKey="Suska F">F Suska</name></author><author><name sortKey="Lenner S, M" uniqKey="Lenner S M">M Lennerås</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="H Gi, Tt" uniqKey="H Gi T">TT Hägi</name></author><author><name sortKey="Enggist, L" uniqKey="Enggist L">L Enggist</name></author><author><name sortKey="Michel, D" uniqKey="Michel D">D Michel</name></author><author><name sortKey="Ferguson, Sj" uniqKey="Ferguson S">SJ Ferguson</name></author><author><name sortKey="Liu, Y" uniqKey="Liu Y">Y Liu</name></author><author><name sortKey="Hunziker, Eb" uniqKey="Hunziker E">EB Hunziker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stein, Gs" uniqKey="Stein G">GS Stein</name></author><author><name sortKey="Lian, Jb" uniqKey="Lian J">JB Lian</name></author><author><name sortKey="Van Wijnen, Aj" uniqKey="Van Wijnen A">AJ Van Wijnen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Franceschi, Rt" uniqKey="Franceschi R">RT Franceschi</name></author><author><name sortKey="Xiao, G" uniqKey="Xiao G">G Xiao</name></author><author><name sortKey="Jiang, D" uniqKey="Jiang D">D Jiang</name></author><author><name sortKey="Gopalakrishnan, R" uniqKey="Gopalakrishnan R">R Gopalakrishnan</name></author><author><name sortKey="Yang, S" uniqKey="Yang S">S Yang</name></author><author><name sortKey="Reith, E" uniqKey="Reith E">E Reith</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lee, Mh" uniqKey="Lee M">MH Lee</name></author><author><name sortKey="Kim, Yj" uniqKey="Kim Y">YJ Kim</name></author><author><name sortKey="Kim, Hj" uniqKey="Kim H">HJ Kim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kuroda, S" uniqKey="Kuroda S">S Kuroda</name></author><author><name sortKey="Virdi, As" uniqKey="Virdi A">AS Virdi</name></author><author><name sortKey="Dai, Y" uniqKey="Dai Y">Y Dai</name></author><author><name sortKey="Shott, S" uniqKey="Shott S">S Shott</name></author><author><name sortKey="Sumner, Dr" uniqKey="Sumner D">DR Sumner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bromme, D" uniqKey="Bromme D">D Brömme</name></author><author><name sortKey="Lecaille, F" uniqKey="Lecaille F">F Lecaille</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nakahama, Ki" uniqKey="Nakahama K">KI Nakahama</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jimbo, R" uniqKey="Jimbo R">R Jimbo</name></author><author><name sortKey="Xue, Y" uniqKey="Xue Y">Y Xue</name></author><author><name sortKey="Hayashi, M" uniqKey="Hayashi M">M Hayashi</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Norvège</li><li>Suède</li></country></list><tree><country name="Suède"><noRegion><name sortKey="Bougas, Kostas" sort="Bougas, Kostas" uniqKey="Bougas K" first="Kostas" last="Bougas">Kostas Bougas</name></noRegion><name sortKey="Jimbo, Ryo" sort="Jimbo, Ryo" uniqKey="Jimbo R" first="Ryo" last="Jimbo">Ryo Jimbo</name><name sortKey="Wennerberg, Ann" sort="Wennerberg, Ann" uniqKey="Wennerberg A" first="Ann" last="Wennerberg">Ann Wennerberg</name></country><country name="Norvège"><noRegion><name sortKey="Xue, Ying" sort="Xue, Ying" uniqKey="Xue Y" first="Ying" last="Xue">Ying Xue</name></noRegion><name sortKey="Mustafa, Kamal" sort="Mustafa, Kamal" uniqKey="Mustafa K" first="Kamal" last="Mustafa">Kamal Mustafa</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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